Acute viral hepatitis A, B, C cause elevated serum ferritin due to liver inflammation. Hepatitis C causes damage by binding iron, resulting in free radicals that damage liver cells. The liver becomes inflamed, leading to formation of scar tissue and ultimately cirrhosis or liver cancer. Elevated ferritin can be seen in individuals suffering from hemochromatosis, which is a hereditary disorder. Through this article, let’s see the effects of raised ferritin levels on the health of an individual Ferritin is a protein found in the blood that stores iron reserves in the cells.
Jan 18, 2018 · The levels of serum ferritin, an iron storage protein, are elevated during injury and chronic inflammation, and some studies indicate that its levels can be used to assess the progress of non-alcoholic fatty liver disease to tissue scarring fibrosis. Elevated Ferritin is a lot more common for other reasons than you think and is to not be overlooked. Untreated hemochromatosis can be fatal. More often though, the iron overload presents in patients with obesity, chronic inflammation, daily alcohol consumption, heart.
Liver damage can cause high ferritin levels as liver is the main organ that stores ferritin. Very high ferritin levels can be seen in Still's disease, macrophage activation syndrome, and drug induced hypersensitivity, according to the HIGHFERRITIN Web Server. Liver disease: Liver disease is another cause of high ferritin, brought on by altered iron and glucose metabolism. If you are suffering a viral infection associated with hepatitis, you may suffer from elevated ferritin levels as well.
While a low ferritin confirms the presence of iron deficiency, a normal or high ferritin does not exclude iron deficiency since it is an acute phase protein and can be elevated despite Clinical manifestations and diagnosis of hereditary hemochromatosis View in Chinese. Nov 28, 2019 · If a ferritin test shows higher than normal levels, it could indicate that you have a condition that causes your body to store too much iron. It could also point to liver disease, rheumatoid arthritis, other inflammatory conditions or hyperthyroidism. Some types of.
That’s why ferritin levels can be high in people who have liver disease or types of cancer, such as Hodgkin’s lymphoma. For example, liver cells have stored ferritin. Nov 01, 2011 · Understanding the basic disease processes that cause mildly elevated liver transaminase levels i.e., less than five times the upper limit of normal and the epidemiology of each disease can help.
Elevated ferritin is also observed in acute and chronic liver disease, chronic renal failure, and in some types of neoplastic disease. In the presence of conditions such as inflammation, infection, malignancy hematological and solid tumors, or liver or kidney disease, serum ferritin concentrations do not reflect iron stores alone and are typically higher than otherwise expected.
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